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Properties of substance:

GB



skc-file

Synonyms:

EA 1208
sarin
isopropylmethylphosphonofluoridate

Group of substances:

elmentoorganic

Physical appearance:

colorless liquid

Empirical formula (Hill's system for organic substances):

C4H10FO2P

Structural formula as text:

CH3P(O)(F)OCH(CH3)2

Molar/atomic mass: 140.09

Melting point (°C):

-54

Boiling point (°C):

151.5

Decomposition temperature (°C):

160-165

CAS №: 107-44-8


Solubility (g/100 g of solvent):

1,2-dichloroethane: very soluble [Ref.]
acetone: very soluble [Ref.]
ethanol: very soluble [Ref.]
water: miscible [Ref.]

Numerical data:

Year of discovery: 1939
LCt50 (mg·min/l): 0.075

Density:

1.094 (20°C, g/cm3)

Refractive index (nD):

1.383 (20°C)

Vapour pressure (Torr):

1.48 (20°C)

Viscosity (mPa·s):

1.82 (20°C)

LD50 (mg/kg):

0.014 (cats, intramuscular)
0.015 (rabbits, intravenous)
0.035 (rabbits, onto the eye)
0.6 (rats, oral)
0.05 (rats, intravenous)
0.044 (rats, subcutaneous)
0.095 (rats, intramuscular)
0.041 (mice, intravenous)
0.083 (mice, intravenous)
0.1 (mice, subcutaneous)
0.2 (mice, intraperitoneal)
0.025 (monkeys, intravenous)
0.012 (dogs, intravenous)
0.14 (mens, oral)
24 (mens, onto the skin)

References:

  1. Gupta R.C. Handbook of Toxicology of Chemical Warfare Agents. - Elsevier, 2009. - pp. 769
  2. Neilson A.H. The Handbook of Environmental Chemistry. - Vol. 3. - Berlin, 2002. - pp. 321-322
  3. Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents. Volume 1: Anticholinesterases and Anticholinergics. - Washington, 1982. - pp. A1
  4. Александров В.Н., Емельянов В.И. Отравляющие вещества. - 2-е изд., под ред. Сокольского Г.А. - М.: Военное издательство, 1990. - pp. 58-90 [Russian]
  5. Голиков С.Н., Розенгарт В.И. Фармакология и токсикология фосфорорганических соединений. - Л.: Медгиз, 1960. - pp. 8 [Russian]
  6. Головко А.И., Головко С.И., Зефиров С.Ю., Софронов Г.А. Токсикология ГАМК-литиков. - С-Пб.: Нива, 1996. - pp. 39, 81 [Russian]
  7. Краткая химическая энциклопедия. - Т. 2: Ж-Малоновый эфир. - М.: Советская энциклопедия, 1963. - pp. 82 [Russian]
  8. Руководство по токсикологии отравляющих веществ. - Под ред. Голикова С.Н. - М.: Медицина, 1972. - pp. 79, 82. 89 [Russian]
  9. Франке З. Химия отравляющих веществ. - Т.1. - М.: Химия, 1973. - pp. 294 [Russian]
  10. Химическая энциклопедия. - Т. 2. - М.: Советская энциклопедия, 1990. - pp. 162 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru