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Properties of substance:

famotidine



skc-file

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C8H15N7O2S3

Molar/atomic mass: 337.445

Melting point (°C):

163-164

CAS №: 76824-35-6

Solubility (g/100 g of solvent):

acetic acid: very soluble [Ref.]
acetone: practically insoluble [Ref.]
chloroform: practically insoluble [Ref.]
diethyl ether: practically insoluble [Ref.]
dimethylformamide: very soluble [Ref.]
ethanol: practically insoluble [Ref.]
ethyl acetate: practically insoluble [Ref.]
methanol: sparingly soluble [Ref.]
water: 0.00011 (25°C) [Ref.]

LD50 (mg/kg):

244.4 (mice, intravenous)

References:

  1. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 827
  2. The Merck Index 11th ed., Merck & Company, 1989. - pp. 617
  3. Yalkowsky S.H., Yan H., Jain P. Handbook of aqueous solubility data. – 2nd ed. - CRC Press, 2010. - pp. 530
  4. Вартанян Р.С. Синтез основных лекарственных средств. - М.: МИА, 2004. - pp. 326-327 [Russian]
  5. Токсикологический вестник. - 2002. - №3. - pp. 41-42 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru