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Properties of substance:

codeine monohydrate



skc-file

Group of substances:

organic

Physical appearance:

colorless crystals

Empirical formula (Hill's system for organic substances):

C18H23NO4

Molar/atomic mass: 317.39

Decomposition temperature (°C):

100

Solubility (g/100 g of solvent):

benzene: soluble [Ref.]
chloroform: soluble [Ref.]
diethyl ether: 11.3 (25°C) [Ref.]
ethanol: 79.1 (25°C) [Ref.]
water: 0.83 (25°C) [Ref.]
water: 1.7 (80°C) [Ref.]

LD50 (mg/kg):

427 (rats, oral)
75 (rats, intravenous)
250 (mice, oral)
60 (mice, intraperitoneal)

References:

  1. Беликов В.Г. Учебное пособие по фармацевтической химии. - М.: Медицина, 1979. - pp. 374 [Russian]
  2. Справочник химика. - Т. 2. - Л.-М.: Химия, 1964. - pp. 726-727 [Russian]
  3. Токсикологический вестник. - 1995. - №4. - pp. 22 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru