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Properties of substance:

morphine sulfate pentahydrate

Group of substances:

organic

Physical appearance:

colorless needles crystals

Empirical formula (Hill's system for organic substances):

C34H50N2O15S

Molar/atomic mass: 758.87

Decomposition temperature (°C):

250

Solubility (g/100 g of solvent):

diethyl ether: insoluble [Ref.]
ethanol: 0.28 (20°C) [Ref.]
ethanol: 0.53 (60°C) [Ref.]
water: 6.66 (20°C) [Ref.]
water: 166.6 (80°C) [Ref.]

LD50 (mg/kg):

461 (rats, oral)
70 (rats, intravenous)
600 (mice, oral)
156 (mice, intravenous)
316 (dogs, intravenous)

References:

  1. Journal of Medicinal Chemistry. - 1995. - Vol. 38, No. 18. - pp. 3655
  2. Journal of Medicinal Chemistry. - 2003. - Vol. 46, No. 19. - pp. 4184
  3. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 1367
  4. Бабаян Э.А., Гаевский А.В., Бардин Е.В. Правовые аспекты оборота наркотических, психотропных, сильнодействующих, ядовитых веществ и прекурсоров. - М.: МЦФЭР, 2000. - pp. 145 [Russian]
  5. Справочник по растворимости. - Т.1, Кн.2. - М.-Л.: ИАН СССР, 1962. - pp. 1595 [Russian]
  6. Справочник химика. - Т. 2. - Л.-М.: Химия, 1964. - pp. 800-801 [Russian]
  7. Токсикологическая химия. - Под ред. Плетеневой Т.В. - М.: ГЭОТАР-Медиа, 2005. - pp. 27 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru