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Properties of substance:

4-hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide



skc-file

Synonyms:

piroxicam

Group of substances:

organic

Empirical formula (Hill's system for organic substances):

C15H13N3O4S

Molar/atomic mass: 331.346

Melting point (°C):

198-200

CAS ¹: 36322-90-4

Solubility (g/100 g of solvent):

1,4-dioxane: 1.87 (25°C) [Ref.]
water: 0.0023 (25°C) [Ref.]

LD50 (mg/kg):

216 (rats, oral)
250 (mice, oral)
108 (dogs, oral)

References:

  1. Buschmann H., Christoph T., Friderichs E., Maul C., Sundermann B. Analgesics from Chemistry and Pharmacology to Clinical Application. - 2002. - pp. 99
  2. Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 911
  3. Jouyban A. Handbook of solubility data for pharmaceutacals. – CRC Press, 2010. - pp. 72
  4. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 1667-1669
  5. Yalkowsky S.H., Yan H. Handbook of aqueous solubility data. - CRC Press, 2003. - pp. 1002

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru