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Properties of substance:

cardilax



skc-file

Synonyms:

verapamil

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C27H39ClN2O4

Molar/atomic mass: 491.06256

Melting point (°C):

140-145

CAS №: 53-53-9

Solubility (g/100 g of solvent):

chloroform: soluble [Ref.]
methanol: soluble [Ref.]
water: soluble [Ref.]

Dissociation:

pKBH+ (1) = 8.6 (25°C, water)

LD50 (mg/kg):

16 (rats, intravenous)
150 (, oral)
341 (, oral)
5.795 (mice, intravenous)
76 (, intraperitoneal)

References:

  1. Armarego W. L. F. Purification of Laboratory Chemicals. - 5ed. - 2003. - pp. 573-574
  2. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 2162-2163
  3. Регистр лекарственных средств России: Энциклопедия лекарств. - 8 изд. - М., 2001. - pp. 173-174 [Russian]
  4. Токсикологический вестник. - 1996. - №2. - pp. 37 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru