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Properties of substance:

prednisolone



skc-file

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C21H28O5

Molar/atomic mass: 360.444

Melting point (°C):

229

CAS №: 50-24-8

Solubility (g/100 g of solvent):

1,4-dioxane: difficulty soluble [Ref.]
acetone: difficulty soluble [Ref.]
chloroform: sparingly soluble [Ref.]
ethanol: soluble [Ref.]
methanol: soluble [Ref.]
water: 0.05 (30°C) [Ref.]

LD50 (mg/kg):

3879 (, oral)
3857 (, oral)
2848 (, oral)

References:

  1. Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 917-918
  2. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 1693-1695
  3. Yalkowsky S.H., Yan H. Handbook of aqueous solubility data. - CRC Press, 2003. - pp. 1179
  4. Беликов В.Г. Учебное пособие по фармацевтической химии. - М.: Медицина, 1979. - pp. 437 [Russian]
  5. Токсикологический вестник. - 2001. - №5. - pp. 32-33 [Russian]
  6. Химический энциклопедический словарь. - Под ред. Кнунянц И.Л. - М.: Советская энциклопедия, 1983. - pp. 477 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru