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Properties of substance:

physodtigmine salicylate

Group of substances:

organic

Physical appearance:

colorless prismatic crystals

Empirical formula (Hill's system for organic substances):

C23H29N3O4

Structural formula as text:

C16H23N3O * HOC6H4COOH

Molar/atomic mass: 411.494

Melting point (°C):

186

CAS №: 57-64-7

Solubility (g/100 g of solvent):

chloroform: 11.6 (25°C) [Ref.]
diethyl ether: 0.57 (25°C) [Ref.]
ethanol: 7.87 (25°C) [Ref.]
ethanol: 25 (60°C) [Ref.]
water: 1.38 (25°C) [Ref.]
water: 6.66 (80°C) [Ref.]

LD50 (mg/kg):

2.5 (mice, oral)

References:

  1. Buckingham J. B., Baggaley K. H., Roberts A. D., Szabo L. F. Dictionary of Alkaloids. - 2 ed. - CRC Press, 2010. - pp. 1521
  2. Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 900
  3. Gangolli S. The Dictionary of Substances and their Effects. - 2 ed., Vol. 6, O-S. - RSC, 1999. - pp. 362-363
  4. Seidell A. Solubilities of organic compounds. - 3ed., vol.2. - New York: D. Van Nostrand Company, 1941. - pp. 758
  5. Беликов В.Г. Учебное пособие по фармацевтической химии. - М.: Медицина, 1979. - pp. 381 [Russian]
  6. Справочник по растворимости. - Т.1, Кн.2. - М.-Л.: ИАН СССР, 1962. - pp. 1589 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru