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Properties of substance:

dl-amphetamine



skc-file

Group of substances:

organic

Physical appearance:

colorless mobile liquid

Empirical formula (Hill's system for organic substances):

C9H13N

Structural formula as text:

C6H5CH2CH(NH2)CH3

Molar/atomic mass: 135.206

Boiling point (°C):

204

CAS №: 300-62-9

Solubility (g/100 g of solvent):

chloroform: soluble [Ref.]
diethyl ether: very soluble [Ref.]
ethanol: soluble [Ref.]
water: 2 (20°C) [Ref.]

Density:

0.93 (20°C, g/cm3)

Refractive index (nD):

1.518 (26°C)

Vapour pressure (Torr):

0.75 (33°C)
7 (64°C)
7.5 (70.1°C)
75 (118°C)
750 (202°C)

Dissociation:

pKBH+ (1) = 9.9 (20°C, water)

LD50 (mg/kg):

39 (rats, subcutaneous)
125 (rats, intraperitoneal)
22 (mice, oral)
18 (mice, intravenous)
2.8 (mice, subcutaneous)
16 (mice, intraperitoneal)

References:

  1. CRC Handbook of Chemistry and Physics. - 95ed. - CRC Press, 2014. - pp. 3-456
  2. Clarke's Analysis of Drugs and Poisons. - 4 ed. - London, 2011. - pp. 871-875
  3. Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 349-350
  4. Elks J., Ganellin C.R. Dictionary of Drugs: Chemical Data, Structures and Bibliographies. - Springer, 1990. - pp. 970
  5. Gangolli S. The Dictionary of Substances and their Effects. - 2 ed., Vol. 1, A-B. - RSC, 1999. - pp. 292-293
  6. Landolt-Bornstein Numerical Data and Functional Relationships in Science and Technology. Group IV, Volume 20: Vapor Pressure of Chemicals. Subvolume C: Vapor Pressure and Antoine Constants for Nitrogen Containing Organic Compounds 2001. - pp. 95
  7. Lewis R.J. Sax's Dangerous Properties of Industrial Materials. - 11ed. - Wiley-interscience, 2004. - pp. 245, 358
  8. Бабаян Э.А., Гаевский А.В., Бардин Е.В. Правовые аспекты оборота наркотических, психотропных, сильнодействующих, ядовитых веществ и прекурсоров. - М.: МЦФЭР, 2000. - pp. 145 [Russian]
  9. Полюдек-Фабини Р., Бейрих Т. Органический анализ. - Л.: Химия, 1981. - pp. 280 [Russian]
  10. Регистр лекарственных средств России: Энциклопедия лекарств. - 8 изд. - М., 2001. - pp. 85 [Russian]
  11. Справочник химика. - Т. 2. - Л.-М.: Химия, 1964. - pp. 1034-1035 [Russian]
  12. Химический энциклопедический словарь. - Под ред. Кнунянц И.Л. - М.: Советская энциклопедия, 1983. - pp. 610 [Russian]
  13. Хирц Ж. Аналитические методы исследования метаболизма лекарственных средств. - М.: Медицина, 1975. - pp. 26-30 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru