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Properties of substance:

baclofen



skc-file

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C10H12ClNO2

Structural formula as text:

ClC6H4CH(CH2NH2)CH2COOH

Molar/atomic mass: 213.66

Melting point (°C):

207

CAS №: 1134-47-0

Solubility (g/100 g of solvent):

water: 0.4549 (25°C) [Ref.]

LD50 (mg/kg):

145 (rats, oral)
78 (rats, intravenous)
200 (mice, oral)
31 (mice, intravenous)

References:

  1. Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 369-370
  2. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 174-175
  3. Yalkowsky S.H., Yan H. Handbook of aqueous solubility data. - CRC Press, 2003. - pp. 659
  4. Машковский М.Д. Лекарственные средства. - 15-е изд. - М.: Новая волна, 2007. - pp. 46-47 [Russian]
  5. Регистр лекарственных средств России: Энциклопедия лекарств. - 8 изд. - М., 2001. - pp. 119 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru