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Properties of substance:

apomorphine hydrochloride



skc-file

Group of substances:

organic

Physical appearance:

monoclinic crystals

Empirical formula (Hill's system for organic substances):

C17H18ClNO2

Molar/atomic mass: 303.783

Melting point (°C):

200

Solubility (g/100 g of solvent):

chloroform: 0.026 (25°C) [Ref.]
diethyl ether: 0.0755 (25°C) [Ref.]
ethanol: 3.13 (25°C) [Ref.]
ethanol 90%: 2 (25°C) [Ref.]
water: 1.7 (15°C) [Ref.]

Reactions of synthesis:

  1. [Ref.1]

LD50 (mg/kg):

38 (mice, intravenous)
0.145 (mice, intraperitoneal)

References:

  1. CRC Handbook of Chemistry and Physics. - 95ed. - CRC Press, 2014. - pp. 3-30
  2. Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 357
  3. Lewis R.J. Sax's Dangerous Properties of Industrial Materials. - 11ed. - Wiley-interscience, 2004. - pp. 287
  4. Seidell A. Solubilities of organic compounds. - 3ed., vol.2. - New York: D. Van Nostrand Company, 1941. - pp. 769, 773
  5. Справочник по растворимости. - Т.1, Кн.2. - М.-Л.: ИАН СССР, 1962. - pp. 1574 [Russian]
  6. Справочник химика. - Т. 2. - Л.-М.: Химия, 1964. - pp. 444-445 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru