Main page (Russian) Search in database (English)

Properties of substance:

apomorphine



skc-file

Group of substances:

organic

Physical appearance:

colorless prismatic crystals

Empirical formula (Hill's system for organic substances):

C17H17NO2

Molar/atomic mass: 267.322

Melting point (°C):

170

CAS №: 58-00-4

Solubility (g/100 g of solvent):

acetone: soluble [Ref.]
benzene: soluble [Ref.]
chloroform: soluble [Ref.]
diethyl ether: soluble [Ref.]
ethanol: soluble [Ref.]
olive oil: 5 (25°C) [Ref.]
water: 0.01069 (15°C) [Ref.]

Dissociation:

pKBH+ (1) = 8.92 (25°C, water)
pKBH+ (2) = 7 (25°C, water)

LD50 (mg/kg):

56 (mice, intravenous)

References:

  1. CRC Handbook of Chemistry and Physics. - 95ed. - CRC Press, 2014. - pp. 3-30
  2. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 130-131
  3. Lewis R.J. Sax's Dangerous Properties of Industrial Materials. - 11ed. - Wiley-interscience, 2004. - pp. 287
  4. Neve K.A. The Dopamine Receptors. - 2ed. - Humana Press, 2010. - pp. 76-77
  5. New, centrally acting dopaminergic agents with an improved oral bioavailability: synthesis and pharmacological evaluation. - 2000. - pp. 95
  6. Yalkowsky S.H., Yan H. Handbook of aqueous solubility data. - CRC Press, 2003. - pp. 1072
  7. Новый справочник химика и технолога. Радиоактивные вещества. Вредные вещества. Гигиенические нормативы. - СПб.: НПО Профессионал, 2007. - pp. 817 [Russian]
  8. Справочник по растворимости. - Т.1, Кн.2. - М.-Л.: ИАН СССР, 1962. - pp. 1576 [Russian]
  9. Справочник химика. - Т. 2. - Л.-М.: Химия, 1964. - pp. 444-445 [Russian]

    What information do you need?




    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru