Main page (Russian) Search in database (English)

Properties of substance:

GR 89696



skc-file

Group of substances:

organic

Empirical formula (Hill's system for organic substances):

C23H29Cl2N3O7

Molar/atomic mass: 530.398

Melting point (°C):

178-179

Numerical data:

κ-Opioid Receptor Binding (nM): 0.041

References:

  1. Naylor A., Judd D.B., Lloyd J.E., Scopes D.I.C., Hayes A.G., Birch P.J. A Potent New Class of κ-Receptor Agonist: 4-Substituted 1-(Arylacetyl)-2-[(dialkylamino)methyl]piperazines / Journal of Medicinal Chemistry. - 1993. - Vol. 36, No. 15. - pp. 2075-2083
  2. Caudle R.M., Mannes A.J., Iadarola M.J. GR89,696 Is a Kappa-2 Opioid Receptor Agonist and a Kappa-1 Opioid Receptor Antagonist in the Guinea Pig Hippocampus / Journal of Pharmacology and Experimental Therapeutics. - 1997. - Vol. 283, №3. - pp. 1342-1349
  3. Токсикологический вестник. - 2011. - №3. - pp. 13-16 [Russian]

    What information do you need?




    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru